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2 live roles

1099
NP jobs in Missouri.

1099 NP jobs in Missouri

1099 Positions in Missouri (2)

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Prescribing Nurse Practitioner or Physician Assistant · Columbia, MO · 1099 Contract

Lyra Health

Columbia, Missouri

ContractIn-Person

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L

Prescribing Nurse Practitioner or Physician Assistant · Holliday, MO · 1099 Contract

Lyra Health

Holliday, Missouri

ContractIn-Person

View Job →

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New 1099 NP positions in Missouri, delivered daily.

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1099 Tips

  • •Form an LLC or PLLC before signing your first contract
  • •Set aside part of every payment for quarterly estimated taxes
  • •Maintain your own malpractice insurance (occurrence-based)
  • •Track all business expenses diligently for tax deductions
  • •Work with a healthcare-specialized CPA for tax planning

Why 1099?

Gross Versus Net

Contractor rates are quoted before self-employment tax, malpractice, and the benefits you fund yourself. Model the after-tax figure before comparing to W-2 pay.

Schedule Control

Set your own hours, work with multiple clients, and control your patient volume and caseload.

Business Structure

Business expenses and retirement contributions are handled as a self-employed clinician. An accountant who works with clinicians can map what applies to you.

Hiring in Missouri

1099 Careers in Missouri

Independent-contractor (1099) NP listings for Missouri quote a rate before self-employment tax, malpractice, and the benefits you fund yourself. Model the after-tax figure, and confirm who holds any collaborative agreement Missouri requires before signing. NP Hiring currently lists 2 active postings for Missouri in this category.

The newest listing was posted on August 26, 2026.

1099 NP
Employers

Who is hiring

All 2 current 1099 listings in Missouri are posted by Lyra Health.

Locations

Where the listings are

Listings with a stated location are spread across 2 cities, led by Columbia (1) and Holliday (1).

Restricted Practice

Licensure and practice rules in Missouri

AANP classifies Missouri as a restricted practice state. Missouri requires NPs to have a collaborative practice arrangement with physician supervision.

Missouri is a Nurse Licensure Compact member. The compact covers the RN license beneath your APRN credential. The APRN license itself is still issued by Missouri.

Applications, fees and renewal rules come from the Missouri State Board of Nursing.

Sources: AANP State Practice Environment (practice authority); NCSBN Nurse Licensure Compact roster (verified August 11, 2026). Counts come from live listings on this board, recounted October 24, 2026.

Common Questions

1099 NP Jobs in Missouri FAQ

How many 1099 NP jobs are open in Missouri?

All 2 current 1099 listings in Missouri are posted by Lyra Health. The newest listing was posted on August 26, 2026.

Do NPs need a collaborating or supervising physician in Missouri?

Yes. Missouri requires NPs to have a collaborative practice arrangement with physician supervision. The Missouri State Board of Nursing publishes the current rule.

Is Missouri part of the Nurse Licensure Compact?

Yes, Missouri is a Nurse Licensure Compact member (verified against the live NCSBN roster, August 11, 2026). The compact covers the RN license underpinning your APRN credential (a multistate RN license works across member states), but APRN licensure itself is still issued individually by each state, including Missouri.