1099 Positions in South Carolina (1)
View All Jobs1099 Tips
- •Form an LLC or PLLC before signing your first contract
- •Set aside part of every payment for quarterly estimated taxes
- •Maintain your own malpractice insurance (occurrence-based)
- •Track all business expenses diligently for tax deductions
- •Work with a healthcare-specialized CPA for tax planning
Why 1099?
Contractor rates are quoted before self-employment tax, malpractice, and the benefits you fund yourself. Model the after-tax figure before comparing to W-2 pay.
Set your own hours, work with multiple clients, and control your patient volume and caseload.
Business expenses and retirement contributions are handled as a self-employed clinician. An accountant who works with clinicians can map what applies to you.
Hiring in South Carolina
1099 Careers in South Carolina
Who is hiring
The only current 1099 listing in South Carolina is posted by Lyra Health.
- Lyra Health1 listing
Where the listings are
Every listing with a stated location is in Conway.
Licensure and practice rules in South Carolina
AANP classifies South Carolina as a restricted practice state. South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation.
South Carolina is a Nurse Licensure Compact member. The compact covers the RN license beneath your APRN credential. The APRN license itself is still issued by South Carolina.
Applications, fees and renewal rules come from the South Carolina Board of Nursing.
Sources: AANP State Practice Environment (practice authority); NCSBN Nurse Licensure Compact roster (verified August 11, 2026). Counts come from live listings on this board, recounted October 24, 2026.
More job types in South Carolina
Common Questions
1099 NP Jobs in South Carolina FAQ
How many 1099 NP jobs are open in South Carolina?
The only current 1099 listing in South Carolina is posted by Lyra Health. The newest listing was posted on August 26, 2026.
Do NPs need a collaborating or supervising physician in South Carolina?
Yes. South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation. The South Carolina Board of Nursing publishes the current rule.
Is South Carolina part of the Nurse Licensure Compact?
Yes, South Carolina is a Nurse Licensure Compact member (verified against the live NCSBN roster, August 11, 2026). The compact covers the RN license underpinning your APRN credential (a multistate RN license works across member states), but APRN licensure itself is still issued individually by each state, including South Carolina.


