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12 live roles

NP
Jobs in South Carolina.

Illustrated diorama representing South Carolina

Positions in South Carolina (12)

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Psychiatric Nurse Practitioner (PMHNP)

LifeStance Health

Rock Hill, SC

$142k to $190k/yrFull-TimeHybrid

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Psychiatric Nurse Practitioner (PMHNP) · Child/Adolescent

LifeStance Health

North Charleston, SC

$142k to $190k/yrFull-TimeHybrid

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Psychiatric Nurse Practitioner (PMHNP)

LifeStance Health

St. Andrews (Columbia), SC

$142k to $190k/yrFull-TimeHybrid

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Psychiatric Nurse Practitioner (PMHNP) · Child/Adolescent

LifeStance Health

Charleston, SC

$142k to $190k/yrFull-TimeHybrid

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Psychiatric Nurse Practitioner (PMHNP) · Child/Adolescent

LifeStance Health

Cayce, SC

$142k to $190k/yrFull-TimeHybrid

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Psychiatric Nurse Practitioner (PMHNP) · Child/Adolescent

LifeStance Health

Columbia, SC

$142k to $190k/yrFull-TimeHybrid

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Psychiatric Nurse Practitioner (South Carolina)

SonderMind

Columbia, South Carolina

$200/hrContractHybrid

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Part Time Remote Psychiatric Nurse Practitioner · Fee For Service

Thriveworks

SC · Remote

$65k to $94k/yrFull-TimeRemote

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Remote Psychiatric Nurse Practitioner · Fee For Service

Thriveworks

SC · Remote

$130k to $187k/yrFull-TimeRemote

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Advanced Practice Provider (APP · PMHNP/PA) · Access Bridge Care Clinic

Medical University of South Carolina

Remote · South Carolina

Full-TimeRemote

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Medical University of South Carolina Leatherman Behavioral Health PRN Advanced Practice Provider (APP · NP/PA)- Florence, SC

Medical University of South Carolina

Florence, SC

Part-TimeIn-Person

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Prescribing Nurse Practitioner or Physician Assistant · Conway, SC · 1099 Contract

Lyra Health

Conway, South Carolina

ContractIn-Person

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Employers

Who is hiring in South Carolina

The employers with the most open NP roles in South Carolina right now are LifeStance Health (6 roles), Medical University of South Carolina (2) and Thriveworks (2). 2 other employers account for the remaining 2 postings.

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Where the NP roles in South Carolina are

Locations

Where in South Carolina the roles are

Open roles are spread across 8 cities. Columbia leads with 2, followed by Cayce (1) and Charleston (1). Cities with fewer than 3 open roles: Conway, Florence, North Charleston, Rock Hill and St. Andrews.

Open roles by category

By category, Psychiatric Mental Health has 10 open roles, Full-Time has 9 and Remote has 3.

A posting can count toward more than one category, for example a remote full-time role counts in both.

South Carolina Overview

Working as an NP in South Carolina

South Carolina currently has 12 active nurse practitioner postings from 5 employers, with hiring concentrated in Columbia, Cayce, and Charleston. By posting volume, the most active categories right now are Psychiatric Mental Health, Full-Time, and Remote. On the regulatory side, AANP places South Carolina in its restricted practice category. AANP uses this category where state law restricts the ability of NPs to engage in at least one element of NP practice, for example through supervision, delegation or team management by another health provider. States in the same category still set different requirements, so check the South Carolina rules themselves before applying. No median is published for South Carolina postings yet, so compare compensation posting by posting. South Carolina's Nurse Licensure Compact membership covers the RN license beneath the APRN credential. The APRN license itself is still issued by South Carolina.

Practice Authority

South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation.

AANP classification: Restricted Practice
Pay

Posted pay in South Carolina

8 postings in South Carolina state a salary, but they come from only 2 employers. A state median appears once postings from at least 3 employers do. The national median for nurse practitioners is $132,300 (BLS OEWS, Nurse Practitioners (29-1171), median annual wage, May 2025).

See the South Carolina salary guide

Work mode and schedule

3Remote
7Hybrid
2On site

3 of 12 open roles are remote, 7 are hybrid and 2 are on site.

Where employers list a schedule, Full-Time leads with 9, then Contract (2) and Part-Time (1).

Remote roles still name the states they require licensure in, so check each posting before applying.

How current the listings are

4 of 12 open roles were posted in the last 7 days and 9 in the last 30 days. The newest was posted on October 23, 2026.

Counts on this page refresh hourly from active postings.

Licensure and nearby states

Practicing in South Carolina

Licensure path in South Carolina

  1. Verify your RN license foundation
  2. Complete an accredited graduate program
  3. Pass national board certification
  4. Apply for APRN licensure with the South Carolina Board of Nursing
  5. Confirm the practice requirements that apply to you
  6. Register for federal identifiers

Forms, fees and processing times change, so work from the South Carolina Board of Nursing checklist.

Nearby states with open NP roles on this site, with AANP's classification of each: North Carolina (18 roles, Restricted Practice) and Georgia (13 roles, Restricted Practice).

If you live near a state line, check each state's own practice rules before applying, not just its AANP classification. They shape how a role is structured and what paperwork you file.

Nearby states with open NP roles
StateAANP classificationCompact statusOpen NP roles
North CarolinaRestricted PracticeCompact State18
GeorgiaRestricted PracticeCompact State13

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More NP Opportunities in South Carolina

FAQ

NP Jobs in South Carolina

How many NP jobs are in South Carolina?+

There are 12 open NP roles in South Carolina on NP Hiring. By category, Psychiatric Mental Health has 10 open roles, Full-Time has 9 and Remote has 3. Counts refresh hourly.

What is the practice authority in South Carolina?+

AANP classifies South Carolina as a restricted practice state. South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation.

What is the median NP salary in South Carolina?+

8 postings in South Carolina state a salary, but they come from only 2 employers. A state median appears once postings from at least 3 employers do. The national median for nurse practitioners is $132,300 (BLS OEWS, Nurse Practitioners (29-1171), median annual wage, May 2025).

Which cities in South Carolina have the most NP jobs?+

Columbia has the most open NP roles in South Carolina (2), followed by Cayce (1) and Charleston (1).

Which employers are hiring NPs in South Carolina?+

The employers with the most open NP roles in South Carolina right now are LifeStance Health (6 roles), Medical University of South Carolina (2) and Thriveworks (2). 2 other employers account for the remaining 2 postings.

Are remote NP roles available in South Carolina?+

3 of 12 open South Carolina roles are listed as remote. Each posting names the states it requires licensure in.

How do I get licensed as an NP in South Carolina?+

The first steps are to verify your RN license foundation and complete an accredited graduate program. Applications run through the South Carolina Board of Nursing.