Full-Time Positions in Charleston (8)
View All JobsAdvanced Practice Nurse (Nurse Practitioner) · Specialty Care
Charleston, South Carolina
Psychiatric Nurse Practitioner (PMHNP) · Child/Adolescent
Charleston, SC
Nurse Practitioner or Physician Assistant · Gastroenterology & Hepatology
Charleston, SC
Nurse Practitioner or Physician Assistant · HemOnc Infusion
Charleston, SC
Full time CRNA with Peds experience need in SC
Charleston, South Carolina
UNIV-Advanced Practice Provider- (PMHNP-BC) Residency-College of Nursing
Charleston
Nurse Practitioner or Physician Assistant · Neonatology
Charleston
Nurse Practitioner or Physician Assistant · Hematology Oncology
Charleston
APP Manager · Critical Care, CTICU Department of Anesthesia and Perioperative Medicine
Charleston
Full-Time Tips
- •Ask whether a sign-on bonus is offered and how it vests
- •Ask about panel size and daily visit expectations
- •Clarify on-call requirements before accepting
- •Review non-compete clauses carefully
- •Confirm CME budget and time-off allowance
Why Choose Full-Time
Full-Time Careers in Charleston
9 of the 9 listings were first posted in the last 30 days. The most recent was first posted on November 13, 2026.
Practicing as an NP in South Carolina
AANP classifies South Carolina as a restricted practice state. South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation. South Carolina is a Nurse Licensure Compact member. The compact covers the RN license beneath your APRN credential. The APRN license itself is still issued by South Carolina. APRN licensure is issued by the South Carolina Board of Nursing. Check the board's current checklist before accepting a role, because requirements and fees change. Certification for this role: national board certification through AANPCB or ANCC on the population track that matches the role.
Comprehensive Benefits
Health, dental and vision coverage, retirement plans and paid time off are usually part of the offer. Confirm each in the listing.
Job Security
Stable employment with consistent income, malpractice coverage, and professional development support.
Career Growth
Access to leadership tracks, CME funding and promotion paths. Ask how each is structured.
Posted pay for full-time roles
3 of 8 listings state an annual salary. A median appears once at least 5 listings from 3 employers do, with no single employer above 40% of them. Until then, compare pay listing by listing. Nationally, nurse practitioners earn a median annual wage of $132,300 (BLS OEWS, Nurse Practitioners (29-1171), median annual wage, May 2025).
How these roles are set up
1 of 9 is hybrid and 8 on site.
Local Insights
Charleston at a Glance
Who is hiring
4 employers have active full-time listings in Charleston. Medical University of South Carolina leads with 6.
- Medical University of South Carolina6 listings
- All Star Healthcare Solutions1 listing
- LifeStance Health1 listing
- Veterans Health Administration1 listing
Full-Time roles across South Carolina
Charleston accounts for 8 of the 50 active full-time listings in South Carolina. Other South Carolina cities with full-time listings: Columbia (5) and Greenville (3).
Keep Exploring
Other NP Job Types in Charleston
Full-Time NP Market in Charleston, SC
Full-time NP listings in Charleston are permanent roles where benefits, paid time off, and continuing education support form part of the offer. Compare the whole package rather than base pay alone, and get on-call expectations in writing. Charleston, SC is a mid-sized regional hub in South Carolina by 2020 Census population. AANP places South Carolina in its restricted practice category. States in the same category still set different requirements, so check the South Carolina rules before applying. 8 active NP positions are currently listed on this page.
Sources: U.S. Census Bureau (2020 population); AANP State Practice Environment (as of 2026); NCSBN Nurse Licensure Compact roster (nursecompact.com), verified 2026-08-11; BLS OEWS, Nurse Practitioners (29-1171), median annual wage, May 2025. Listing counts, employers and pay figures come from active listings on this board.
Common Questions