Full-Time Positions in Sioux Falls (7)
View All JobsNurse Practitioner or Physician Assistant | Orthopedics | Outreach
Sioux Falls, SD
Certified Nurse Midwife | Hospitalist
Sioux Falls, SD
Nurse Practitioner or Physician Assistant | ENT
Sioux Falls, SD
Nurse Practitioner | Neonatal
Sioux Falls, SD
Nurse Practitioner or Physician Assistant | Hematology and Transplant | Inpatient
Sioux Falls, SD
Nurse Practitioner or Physician Assistant | Orthopedics | Outreach
Sioux Falls, South Dakota
Certified Nurse Midwife | Hospitalist
Sioux Falls, South Dakota
Certified Registered Nurse Anesthetist (CRNA)
Sioux Falls, South Dakota
Full-Time Tips
- •Ask whether a sign-on bonus is offered and how it vests
- •Ask about panel size and daily visit expectations
- •Clarify on-call requirements before accepting
- •Review non-compete clauses carefully
- •Confirm CME budget and time-off allowance
Why Choose Full-Time
Full-Time Careers in Sioux Falls
8 of the 8 listings were first posted in the last 30 days. The most recent was first posted on November 14, 2026.
Practicing as an NP in South Dakota
AANP classifies South Dakota as a full practice state. South Dakota NPs need a written collaborative agreement with a physician, certified nurse practitioner or certified nurse midwife licensed in South Dakota until they have completed 1,040 hours of licensed practice. After that, they can practice without a collaborative agreement. South Dakota is a Nurse Licensure Compact member. The compact covers the RN license beneath your APRN credential. The APRN license itself is still issued by South Dakota. APRN licensure is issued by the South Dakota Board of Nursing. Check the board's current checklist before accepting a role, because requirements and fees change. Certification for this role: national board certification through AANPCB or ANCC on the population track that matches the role.
Comprehensive Benefits
Health, dental and vision coverage, retirement plans and paid time off are usually part of the offer. Confirm each in the listing.
Job Security
Stable employment with consistent income, malpractice coverage, and professional development support.
Career Growth
Access to leadership tracks, CME funding and promotion paths. Ask how each is structured.
Posted pay for full-time roles
2 of 7 listings state an annual salary. A median appears once at least 5 listings from 3 employers do, with no single employer above 40% of them. Until then, compare pay listing by listing. Nationally, nurse practitioners earn a median annual wage of $132,300 (BLS OEWS, Nurse Practitioners (29-1171), median annual wage, May 2025).
How these roles are set up
All 8 are on site.
Local Insights
Sioux Falls at a Glance
Who is hiring
2 employers have active full-time listings in Sioux Falls. Avera Health leads with 7.
- Avera Health7 listings
- AMN Healthcare1 listing
Full-Time roles across South Dakota
Sioux Falls accounts for 7 of the 40 active full-time listings in South Dakota. Other South Dakota cities with full-time listings: Pierre (3).
Full-Time NP Jobs in Nearby Cities
Keep Exploring
Other NP Job Types in Sioux Falls
Full-Time NP Market in Sioux Falls, SD
Full-time NP listings in Sioux Falls are permanent roles where benefits, paid time off, and continuing education support form part of the offer. Compare the whole package rather than base pay alone, and get on-call expectations in writing. Sioux Falls, SD is a mid-sized regional hub in South Dakota by 2020 Census population. AANP places South Dakota in its full practice category. States in the same category still set different requirements, so check the South Dakota rules before applying. 7 active NP positions are currently listed on this page.
Sources: U.S. Census Bureau (2020 population); AANP State Practice Environment (as of 2026); NCSBN Nurse Licensure Compact roster (nursecompact.com), verified 2026-08-11; BLS OEWS, Nurse Practitioners (29-1171), median annual wage, May 2025. Listing counts, employers and pay figures come from active listings on this board.
Common Questions