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Massachusetts: Full Practice, has enacted but not implemented the Nurse Licensure Compact. Massachusetts grants full practice authority to NPs once they attest to the Board of Registration in Nursing that they have completed at least two years of supervised practice; until then, a qualified healthcare professional, who may be a physician or an experienced NP, supervises their prescribing. NPs applying by reciprocity who have at least two years of NP practice outside Massachusetts, independent or supervised, may instead prescribe without supervision once they attest to that experience.

Maine: Full Practice, a Nurse Licensure Compact member. Maine NPs may prescribe from licensure, including controlled substances in schedules II through V, but must practice for at least 24 months under the supervision of a licensed physician or a supervising NP, or be employed by a clinic or hospital whose medical director is a licensed physician, before practicing independently. A 2026 law replaces this requirement once the Board of Nursing adopts new practice standards by rule, so confirm the current requirement with the Board.