Acute Care Positions in South Carolina (3)
View All JobsNurse Practitioner · Pediatrics Acute Care
Greenville, SC
Medical University of South Carolina Pulmonology and Critical Care Advanced Practice Provider (NP/PA)- Florence, SC
Florence, SC
APP Manager · Critical Care, CTICU Department of Anesthesia and Perioperative Medicine
Charleston
Acute Care Tips
- •Ask about orientation length, procedure training, and overnight support
- •Negotiate shift differentials for nights, weekends, and holidays
- •Clarify patient load per shift and escalation/backup structures
- •Confirm credentialing and privileging timelines before your start date
- •ICU, ED, or step-down RN experience strengthens candidacy, so highlight it
Why Acute Care?
ICUs, step-down units, and hospital specialty services, serving complex adult patients.
Lines, airway support, and bedside procedures within hospital privileges.
Hospital services run around the clock, so shift patterns and differentials are part of the offer. Confirm both in each listing.
Hiring in South Carolina
Acute Care Careers in South Carolina
Who is hiring
3 listings in South Carolina come from 2 employers. Medical University of South Carolina has the most, with 2.
- Medical University of South Carolina2 listings
- Prisma Health1 listing
Where the listings are
Listings with a stated location are spread across 3 cities, led by Charleston (1), Florence (1) and Greenville (1).
How these roles are set up
1 of 3 is hybrid and 2 on site.
Full-Time is the most common arrangement (3).
Licensure and practice rules in South Carolina
AANP classifies South Carolina as a restricted practice state. South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation.
South Carolina is a Nurse Licensure Compact member. The compact covers the RN license beneath your APRN credential. The APRN license itself is still issued by South Carolina.
Applications, fees and renewal rules come from the South Carolina Board of Nursing.
Sources: AANP State Practice Environment (practice authority); NCSBN Nurse Licensure Compact roster (verified August 11, 2026). Counts come from live listings on this board, recounted November 15, 2026.
Acute Care NP jobs in nearby states
Common Questions
Acute Care NP Jobs in South Carolina FAQ
How many Acute Care NP jobs are open in South Carolina?
3 listings in South Carolina come from 2 employers. Medical University of South Carolina has the most, with 2. 3 of these 3 listings were posted in the last 30 days, and the newest was posted on October 22, 2026.
Do NPs need a collaborating or supervising physician in South Carolina?
Yes. South Carolina NPs must perform medical acts under a practice agreement with a physician, who must be readily available for consultation. The South Carolina Board of Nursing publishes the current rule.
Is South Carolina part of the Nurse Licensure Compact?
Yes, South Carolina is a Nurse Licensure Compact member (verified against the live NCSBN roster, August 11, 2026). The compact covers the RN license underpinning your APRN credential (a multistate RN license works across member states), but APRN licensure itself is still issued individually by each state, including South Carolina.